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comQ [Thu Jan 21 2016 10:31:58 GMT+0100 (CET)]
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comQ [Thu Jan 21 2016 10:31:58 GMT+0100 (CET)]

prenylation of comG) and surfactin expression (srfA)
locus
BSU31710
pI
4.00
mw
34.00 kDa
function
regulation of quorum sensing
product
prenyltransferase
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence]
  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.8|Protein modification/ other]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.8|Quorum sensing]
  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|genetic competence], [SW|quorum sensing], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|PhoP regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,256,008 -> 3,256,907

    Phenotypes of a mutant

  • the mutation suppresses the mucoid phenotype of ''[protein|search|motA]'' or ''[protein|search|motB]'' mutants due to loss of [protein|search|DegU] phosphorylation and concomitant reduced expression of the ''[protein|search|capB]-[protein|search|capC]-[protein|search|capA]-[protein|search|capE]'' operon [Pubmed|24296669]
  • The protein

    Catalyzed reaction/ biological activity

  • prenylation of [protein|search|ComX] [Pubmed|22878193]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|ComQ]-[protein|search|ComX] [Pubmed|22878193]
  • Expression and Regulation

    Operon

  • ''[protein|search|comQ]-[protein|search|comX]'' [Pubmed|1715859]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|1715859]
  • Regulation

  • induced under conditions of phosphate limitation ([protein|search|PhoP]) [Pubmed|25666134]
  • Regulatory mechanism

  • [protein|search|PhoP]: transcription activation [Pubmed|25666134]
  • References

  • 12067344,25666134,19605685,22878193,11133937,1715859,19114482,24296669,24425772,24788106,25036949,25757097,26787913