phage-derived gamma polyglutamic acid hydrolase, sporulation protein
function
polyglutamic acid degradation
product
phage-derived gamma polyglutamic acid hydrolase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.4|Capsule biosynthesis and degradation][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|capsule biosynthesis and degradation], [SW|sporulation proteins], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|SigK regulon]Gene
Coordinates on the chromosome (coding sequence)
1,915,221 -> 1,915,979
The protein
Catalyzed reaction/ biological activity
hydrolysis of polyglutamic acid [Pubmed|26158264]Protein family
UPF0714 family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|PghB], [protein|search|PghC], [protein|search|PghZ][SW|Domains]
DUF867 [http://pfam.xfam.org/family/PF05908 x], [[gamma-PGA hydrolase domain]] [Pubmed|26158264][SW|Localization]
cell membrane (according to Swiss-Prot)Expression and Regulation
Operon
''pghL'' [Pubmed|16385044][SW|Sigma factor]
[protein|search|SigK] [Pubmed|15699190,16385044]Regulation
expressed during [SW|sporulation] in the mother cell[Pubmed|16385044]expression during spore [SW|germination] is strongly reduced under conditions of osmotic stress [Pubmed|27766092]Additional information
An [ncRNA|search|antisense RNA], '[protein|search|surA]', is predicted for '[protein|search|pghL]' [PubMed|20525796]References
16385044,20525796,26158264,27766092 
