SubtiBank SubtiBank
plsC
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plsC

acyl-ACP:1-acylglycerolphosphate acyltransferase
locus
BSU09540
pI
9.98
mw
21.78 kDa
protein length
199 aa Sequence Blast
gene length
597 bp Sequence Blast
function
biosynthesis of phospholipids
product
acyl-ACP:1-acylglycerolphosphate acyltransferase
essential
yes
ec
2.3.1.51
synonyms
yhdO

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.2|Biosynthesis of lipids] → [category|SW 2.4.2.1|Biosynthesis of fatty acids]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • Gene

    Coordinates
    1,031,395 → 1,031,994

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Structure

  • [PDB|5KYM] (from Thermotoga maritima) [pubmed|28714993]
  • [SW|Localization]

  • cell membrane at the septum [Pubmed|15743965]
  • Expression and Regulation

    Operons

    genes
    [gene|4DF9B105ABA64AFD5106EE75FCC9EFAB52BEFC83|yhdN]-[gene|FC05D5FC95CEDC4B4A04040C86170D185528B9FF|plsC]
    description
    [Pubmed|10220166]

    sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|10220166,15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]
  • regulatory mechanism

  • [protein|FCDE900167AE36377979E0CF7BC33C7F351B95D3|FapR]: repression, [Pubmed|12737802], in [regulon|FCDE900167AE36377979E0CF7BC33C7F351B95D3|FapR regulon]
  • regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|10220166,15805528]
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    Biological materials

    Mutant

  • MGNA-B483 (yhdO::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1482 NBRP B. subtilis, Japan]
  • References

  • 12737802,17557823,24574048,15743965,28714993