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brxA [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]
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brxA [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]

bacilliredoxin
locus
BSU21860
pI
4.00
mw
15.00 kDa
function
de-bacillithiolation of S-bacillithiolated OhrR and MetE
product
bacilliredoxin
essential
no
synonyms
yphP

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]
  • [SW|Categories] containing this gene/protein

  • [SW|resistance against oxidative and electrophile stress]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,300,221 -> 2,300,655

    The protein

    Catalyzed reaction/ biological activity

  • de-bacillithiolation of S-bacillithiolated [protein|search|OhrR] and [protein|search|MetE] [Pubmed|24313874]
  • Protein family

  • scpA family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|search|BrxB]
  • [SW|Domains]

  • contains an CxC redox motif [Pubmed|20308541]
  • Modification

  • S-bacillithiolation upon hypochlorite stress on Cys-53 [Pubmed|21749987]
  • Structure

  • [PDB|3FHK] [Pubmed|19653655]
  • [SW|Interactions]

  • [protein|search|BrxA]-[protein|search|MetE] [Pubmed|24313874]
  • [protein|search|BrxA]-[protein|search|OhrR] [Pubmed|24313874]
  • Expression and Regulation

    Operon

  • ''brxA'' (according to [http://dbtbs.hgc.jp/COG/prom/yphP.html DBTBS])
  • Biological materials

    Mutant

  • CS213 (''[protein|search|brxA]''::''aphA3'', available in [SW|Colin Harwood]'s and [SW|Jörg Stülke]'s labs) [Pubmed|27197833]
  • References

  • 22938038,19653655,20308541,21749987,24313874