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cysL [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]
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cysL [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

transcriptional activator of the cysJ-cysI operon
locus
BSU37650
pI
6.96
mw
34.00 kDa
function
regulation of cysteine biosynthesis
product
transcriptional regulator (LysR family)
essential
no
synonyms
ywfK, ipa-89d

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.4|Sulfur metabolism]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.4|Sulfur metabolism] → [category|SW 2.6.4.2|sulfur metabolism/ general]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
  • [SW|Categories] containing this gene/protein

  • [SW|sulfur metabolism], [SW|transcription factors and their control]
  • This gene is a member of the following [SW|regulons]

  • [SW|CysL regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,864,309 -> 3,865,208

    Phenotypes of a mutant

  • unable to grow with sulfate or sulfite as the only sulfur source [Pubmed|12169591]
  • The protein

    Protein family

  • [SW|LysR family]
  • Expression and Regulation

    Operon

  • ''cysL'' [Pubmed|12169591]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|12169591]
  • Regulation

  • repressed by sulfate, sulfite, and thiosulfate ([protein|search|CysL]) [Pubmed|12169591]
  • Regulatory mechanism

  • [protein|search|CysL]: auto-repression [Pubmed|12169591]
  • References

  • 12169591