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aldY [2017-05-16 10:26:33]
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aldY [2017-05-16 10:26:33]

aldehyde dehydrogenase (NAD), general stress protein, required for protection against paraquat stress
locus
BSU38830
pI
5.02
mw
52.65 kDa
protein length
485 aa Sequence Blast
gene length
1455 bp Sequence Blast
function
stress resistance
product
aldehyde dehydrogenase (NAD)
essential
no
synonyms
yxkE

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]
  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]
  • Gene

    Coordinates
    3,986,428 → 3,987,885

    The protein

    Protein family

  • aldehyde dehydrogenase family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|EF0AAAF5BAE8E1F54FCA296643F7B9E3CE257B1D|YfmT], [protein|5B66ADB81AB141982F187B1C5E3A9346AA064DE2|YcbD], [protein|A0BEB92D54799956A4ADE106A1388E5710141069|GabD], [protein|1ADC55F8E265AF86E29743C671CE1EA1BE7EB41E|GbsA], [protein|67A72A0EABCD807C25D8EAC61C251142B45C174E|DhaS], [protein|762718A15E5256261D79DF60F9106AF0CE2D60C6|IolA], [protein|2042F691CB37B1BAFE2CF3906A9F7F47457C3995|PutC], [protein|69838717DC6BB27864D88C282BF5BC7CC558BFD7|RocA], [protein|F3341F205CB939498109D2A54DE842065C488DD5|AldX], [protein|99F1FAF28FB4817D94E84BD5288FA33124558933|YwdH]
  • Structure

  • [PDB|4DNG]
  • Expression and Regulation

    Operons

    genes
    [gene|F9CF067A2A8E3B2BACC6A51A0E87E84640349980|aldY]
    description
    [Pubmed|10482513]

    sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|10482513], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]
  • regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|10482513]
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    Biological materials

    Mutant

  • MGNA-B739 (aldY::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1738 NBRP B. subtilis, Japan]
  • References

  • 15805528,10482513,22582280