ylbP

putative N-acetyltransferase

locus: BSU_15100

pI: 5.88

mw: 18.90 kDa

protein length: 160 aa

gene length: 483 bp

function: unknown

product: putative N-acetyltransferase

essential: no

synonyms

Genomic Context

categories

• [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]

Gene

Coordinates: 1,576,767 → 1,577,249

The protein

[SW|Domains]

• [SW|N-acetyltransferase domain] (aa 7-151) (according to UniProt)

[SW|Cofactors]

• CoA [PDB|2PR1]

Structure

• [PDB|2PR1] (in complex with CoA)

Expression and Regulation

Operons

• genes: [gene|F86C3CB8387BB4C3FF9F776EA96E6B5AA2503E2C|ylbP]
  description: [Pubmed|26673679]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|26673679], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

  regulatory mechanism

  • [protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA]: repression, in [regulon|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|CcpA regulon]

  regulation

  • repressed by glucose (10-fold) ([protein|search|CcpA]) [Pubmed|12850135]

Biological materials

Mutant

• MGNA-B253 (ylbP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1252 NBRP B. subtilis, Japan]
• BKE15100 (Δ[gene|F86C3CB8387BB4C3FF9F776EA96E6B5AA2503E2C|ylbP]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE15100 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAACAAATCTCCCCCTTTG, downstream forward: _UP4_TAGAAATCAAAACAACCGGC
• BKK15100 (Δ[gene|F86C3CB8387BB4C3FF9F776EA96E6B5AA2503E2C|ylbP]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK15100 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAACAAATCTCCCCCTTTG, downstream forward: _UP4_TAGAAATCAAAACAACCGGC

References

• 12850135,26673679