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yxdK [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]
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yxdK [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

two-component sensor kinase, regulation of the ABC transporter YxdL-YxdM in response to the cationic antimicrobial peptide, LL-37
locus
BSU39650
pI
6.23
mw
37.00 kDa
function
resistance against toxic peptides
product
two-component sensor kinase
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.2|Protein kinases]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.1|Two-component sensor kinase]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.4|Phosphorylation on a His residue]
  • [SW|Categories] containing this gene/protein

  • [SW|protein modification], [SW|transcription factors and their control], [SW|resistance against toxins/ antibiotics], [SW|membrane proteins], [SW|phosphoproteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    4,071,310 -> 4,072,287

    Phenotypes of a mutant

  • defective in the the ability to support the growth of ''Synechococcus leopoliensis'' CCAP1405/1 on agar media [Pubmed|25875741]
  • The protein

    Catalyzed reaction/ biological activity

  • autophosphorylation, phosphorylation of [protein|search|YxdJ]
  • [SW|Domains]

  • two transmembrane segments, C-terminal histidine phosphotransferase domain
  • Modification

  • autophosphorylation on a His residue
  • Expression and Regulation

    Operon

  • ''[protein|search|yxdJ]-[protein|search|yxdK]'' [Pubmed|10746760]
  • References

  • 10094672,10746760,17600057,21283517,21078927,25875741