SubtiBank SubtiBank
rplE [Fri Jan 29 2016 16:46:42 GMT+0100 (CET)]

rplE [Fri Jan 29 2016 16:46:42 GMT+0100 (CET)]

ribosomal protein
locus
BSU01280
pI
9.00
mw
20.00 kDa
function
translation
product
ribosomal protein L5 (BL6)
essential
yes
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.5|Universally conserved proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|translation], [SW|essential genes], [SW|universally conserved proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|stringent response]
  • Gene

    Coordinates on the chromosome (coding sequence)
    141,195 -> 141,734

    Phenotypes of a mutant

  • essential [Pubmed|23002217,12682299]
  • The protein

    Protein family

  • [SW|ribosomal protein] L5P family (according to Swiss-Prot)
  • Structure

  • [PDB|1IQ4] (Geobacillus stearothermophilus)
  • Expression and Regulation

    Operon

  • ''[protein|search|rpsJ]-[protein|search|rplC]-[protein|search|rplD]-[protein|search|rplW]-[protein|search|rplB]-[protein|search|rpsS]-[protein|search|rplV]-[protein|search|rpsC]-[protein|search|rplP]-[protein|search|rpmC]-[protein|search|rpsQ]-[protein|search|rplN]-[protein|search|rplX]-[protein|search|rplE]-[protein|search|rpsN]-[protein|search|rpsH]-[protein|search|rplF]-[protein|search|rplR]-[protein|search|rpsE]-[protein|search|rpmD]-[protein|search|rplO]'' [Pubmed|9371452]
  • [SW|Sigma factor]

  • [protein|search|SigA] two promoters, about 140bp and 200bp upstream of the start codon [Pubmed|9371452]
  • Regulation

  • [protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]
  • References

  • 8635744,19653700,9371452,11948165,23002217