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yqaM [2018-10-10 17:41:01]
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yqaM [2018-10-10 17:41:01]

similar to phage-related protein, skin-element
locus
BSU26260
pI
5.39
mw
35.98 kDa
protein length
313 aa Sequence Blast
gene length
939 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.3|Skin element]
  • Gene

    Coordinates
    2,693,597 → 2,694,457

    Phenotypes of a mutant

  • overexpression of YqaM causes cell filamentation and abnormal chromosome segregation [Pubmed|20889742]
  • overexpression of YqaM inhibits initiation DNA replication, perhaps due to the interaction with [protein|5CF09E089AA70A32F640CE0D33D1F05312AAE24D|DnaC] [Pubmed|20889742]
  • The protein

    Paralogous protein(s)

  • [protein|8766A2EE18B75E50C5369AB8B72AD934F82D7545|XkdC]
  • Structure

  • [PDB|3ECC] ([protein|5CF09E089AA70A32F640CE0D33D1F05312AAE24D|DnaC], C-terminus of [protein|F301EA8201BF27BAFAD4F95EC3A580A91B970B06|YqaM], corresponds to aa 135 ... 277, 29% identity)
  • [SW|Localization]

  • Cytoplasm (Homogeneous) [Pubmed|16479537]
  • Expression and Regulation

    Operons

    genes
    [gene|16BEDCFFB1671793061ACE4AC528D3B8EB177DC8|yqaF]-[gene|02216407B5EDB98FAF611E22B2323C819B9D58BB|yqdA]-[gene|03DAF537379754763646AF3AF2AD811B107F5302|yqaG]-[gene|F6AB74740776179E77218DB831FEE03773B7353F|yqaH]-[gene|5EA0F507F949D249D5B5B860861BBEB4197E01C5|yqaI]-[gene|CFCCFD8C6420CC1DD076B091AD3D914FC8AB22D5|yqaJ]-[gene|903E11BD2CFF3EE1A831F0F50F91741893C3DAB8|yqaK]-[gene|AB4AF9BD3E16FD72370AFC82CDD1531518053E6F|yqaL]-[gene|F301EA8201BF27BAFAD4F95EC3A580A91B970B06|yqaM]-[gene|A9AACF8F25A1A80B3AE2A94DFC3A0E09012B55E7|yqzO]-[gene|3A89444BA25E4940C4197AACBD8B66BC1C65A493|yqaN]
    description
    [Pubmed|20889742]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|20889742], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • regulatory mechanism

  • [protein|846161AE54F170075F2B2133A8D56FE39A5AF8D9|SknR]: repression, [Pubmed|20889742], in [regulon|846161AE54F170075F2B2133A8D56FE39A5AF8D9|SknR regulon]
  • regulation

  • not expressed during normal growth ([protein|846161AE54F170075F2B2133A8D56FE39A5AF8D9|SknR]) [Pubmed|20889742]
  • additional information

  • A [protein|search|ncRNA] is predicted between [gene|CFCCFD8C6420CC1DD076B091AD3D914FC8AB22D5|yqaJ] and [gene|5EA0F507F949D249D5B5B860861BBEB4197E01C5|yqaI] [PubMed|20525796]
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    Biological materials

    Mutant

  • BKE26260 (Δ[gene|F301EA8201BF27BAFAD4F95EC3A580A91B970B06|yqaM]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE26260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATCCTTACAATAAGGACAAT, downstream forward: _UP4_CAATTAAATCATAGGTTAGG
  • BKK26260 (Δ[gene|F301EA8201BF27BAFAD4F95EC3A580A91B970B06|yqaM]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK26260 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATCCTTACAATAAGGACAAT, downstream forward: _UP4_CAATTAAATCATAGGTTAGG
  • References

  • 20889742,16479537,12060778