yflG [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

methionine aminopeptidase

locus: BSU07690

pI: 5.58

mw: 27.00 kDa

function: removal of N-terminal methionine from nascent proteins

product: methionine aminopeptidase

essential: no

synonyms

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.12|Translation/ other]
• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.1|Protein maturation]

[SW|Categories] containing this gene/protein

• [SW|translation], [SW|protein modification]

Gene

Coordinates on the chromosome (coding sequence): 839,735 -> 840,484

The protein

Catalyzed reaction/ biological activity

• Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides (according to Swiss-Prot)

Protein family

• peptidase M24A family (according to Swiss-Prot)

Paralogous protein(s)

• [protein|search|Map]

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|yflG]-[protein|search|yflH]'' [Pubmed|16207374]

[SW|Sigma factor]

• [protein|search|SigA] [Pubmed|16207374]

Regulatory mechanism

• [protein|search|NagR]: transcription repression (weak and not certain) [Pubmed|16207374]

References

• 16207374