SubtiBank SubtiBank
ywqL [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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ywqL [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

endonuclease V
locus
BSU36170
pI
5.00
mw
26.00 kDa
function
DNA repair
product
endonuclease V
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.5|Newly identified sporulation proteins (based on transcription profiling)]
  • [SW|Categories] containing this gene/protein

  • [SW|DNA repair/ recombination], [SW|sporulation proteins]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,724,420 -> 3,725,136

    Phenotypes of a mutant

  • increased mutation rates [Pubmed|22056936]
  • increased sensitivity of sporulating cells to the genotoxic effects of nitrous acid[Pubmed|27698084]
  • The protein

    Catalyzed reaction/ biological activity

  • Endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate (according to Swiss-Prot)
  • Protein family

  • endonuclease V family (according to Swiss-Prot)
  • Structure

  • [PDB|3GA2]
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''[protein|search|ywqH]-[protein|search|ywqI]-[protein|search|ywqJ]-[protein|search|ywqK]-[protein|search|ywqL]'' [Pubmed|22383849]
  • ''ywqL'' [Pubmed|9353933]
  • Regulation

  • expressed throughout growth and staionary phase [Pubmed|22056936]
  • References

  • 9353933,22056936,22383849,27530626,27698084