comN [2017-8-11 16:0:3]

mediates post-transcriptional control of comE operon expression

locus: BSU27660

pI: 4.62

mw: 11.45 kDa

protein length: 98 aa

gene length: 294 bp

function: regulation of competence and DNA uptake

product: post-transcriptional regulator of comE expression

essential: no

synonyms: yrzD

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence]
• [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence]

Gene

Coordinates: 2,829,152 → 2,829,448

The protein

Catalyzed reaction/ biological activity

• post-transcriptional control of ''[gene|788725411B2E741103603373E43441FD036E1BA0|comEA]'' expression [Pubmed|19028902]
• promotes the accumulation of its target ''[gene|788725411B2E741103603373E43441FD036E1BA0|comEA]'' mRNA to septal and polar sites [Pubmed|22582279]
• required for oriC placement during spore development [Pubmed|27059541]

[SW|Localization]

• localizes to the division site and cell poles in a [protein|A8C0C2B7BCA6FFFF3811402D683FB7B99F7120A4|DivIVA] dependent fashion [Pubmed|22582279]

Expression and Regulation

Operons

• genes: [gene|F21A75744FA0B25D5A251CB57E7A7DC6ABFF1DC7|comN]-[gene|F0E7B6E000A5B06C9023C76F21551E754C8C45BA|secDF]
  description: [pubmed|22383849]

  sigma factors

  • [protein|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM]: sigma factor, [Pubmed|18179421], in [regulon|081DF3EE9FA56209D648C7677188C61CE3AA8E41|SigM regulon]

References

• 19028902,22582279,27059541