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sbcC [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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sbcC [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

DNA exonuclease
locus
BSU10650
pI
5.29
mw
128.00 kDa
function
DNA inter-strand cross-link repair
product
DNA exonuclease
essential
no
synonyms
yirY

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]
  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.7|Genetic competence]
  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.3|Genetic competence]
  • [SW|Categories] containing this gene/protein

  • [SW|DNA repair/ recombination], [SW|genetic competence]
  • This gene is a member of the following [SW|regulons]

  • [SW|ComK regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,144,749 -> 1,148,141

    The protein

    Protein family

  • SbcC subfamily (according to Swiss-Prot)
  • [SW|Localization]

  • Nucleoid (Mid-cell) [Pubmed|16479537]
  • [SW|Interactions]

  • [protein|search|SsbA]-[protein|search|SbcC] [Pubmed|21170359]
  • Expression and Regulation

    Operon

  • ''[protein|search|addB]-[protein|search|addA]-[protein|search|sbcD]-[protein|search|sbcC]-[protein|search|hlpB]'' [Pubmed|22383849]
  • Regulation

  • positive regulation by [protein|search|ComK] [Pubmed|11948146]
  • Biological materials

    Mutant

  • GP894 (''sbcCD''::''kan''), available in [SW|Stülke] lab
  • 1A898 ( ''sbcC''::''cat''), [Pubmed|16780573], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A898&Search=1A898 BGSC]
  • Labs working on this gene/protein

  • [SW|Peter Graumann], Freiburg University, Germany [http://www.biologie.uni-freiburg.de/data/bio2/graumann/index.htm homepage]
  • References

    Reviews

  • 19308706,22933559
  • Original publications

  • 16780573,11948146,16479537,22383849,21170359