SubtiBank SubtiBank
ylmD [2017-06-16 17:27:54]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

ylmD [2017-06-16 17:27:54]

peptidoglycan-editing factor, prevents incorporation of glycine or L-serine into the PG sacculi
locus
BSU15370
pI
6.18
mw
30.79 kDa
protein length
278 aa Sequence Blast
gene length
834 bp Sequence Blast
function
quality control to maintain composition and integrity of peptidoglycan
product
peptidoglycan-editing factor
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan]
  • Gene

    Coordinates
    1,609,327 → 1,610,163

    Phenotypes of a mutant

  • sensitive to ß-lactam antibiotics [pubmed|28612943]
  • The protein

    Protein family

  • UPF0124 family (according to Swiss-Prot)
  • Expression and Regulation

    Operons

    genes
    [gene|ECCE99438DBFC52DA7236CB4F6486DD004CADF73|ylmD]-[gene|31789A170CB624BF8210C915F40007F802F5C81B|ylmE]-[gene|DB09F1C36257F511A84A083967A25A9D46744D14|sepF]-[gene|2B2D285D5A8F160808A21DCF07BDB924365970C5|ylmG]-[gene|BD5ACF930DD63E258D71569326752C9A1D7B9324|ylmH]
    description
    [Pubmed|16420366]

    regulatory mechanism

  • [protein|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A]: repression, [Pubmed|14651647], in [regulon|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A regulon]
  • regulation

  • repressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|14651647]
  • view in new tab

    Biological materials

    Mutant

  • MGNA-B125 (ylmD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1124 NBRP B. subtilis, Japan]
  • References

  • 14651647,16420366,28612943