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padC
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padC

phenolic acid decarboxylase
locus
BSU_34400
pI
4.87
mw
18.93 kDa
protein length
161 aa Sequence Blast
gene length
486 bp Sequence Blast
function
resistance to salicylic acid
product
phenolic acid decarboxylase
essential
no
synonyms
pad,yveH
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.10|Resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)]

    • Gene

    Coordinates
    3,532,325 → 3,532,810

    The protein

    Catalyzed reaction/ biological activity

  • conversion of ferulic acid to 4-vinylguaiacol [Pubmed|26658822]
  • H+ + trans-4-coumarate --> 4-hydroxystyrene + CO2 (according to UniProt)
  • H+ + trans-cinnamate --> CO2 + styrene (according to UniProt)
  • H+ + trans-ferulate --> 2-methoxy-4-vinylphenol + CO2 (according to UniProt)

    • Protein family

  • padC family (single member, according to UniProt)

    • Structure

  • [PDB|2P8G]

    • Expression and Regulation

    Operons

    genes
    [gene|1E0BA378F14ADF03D613DA3BF3241C1ADE75075E|yveF]-[gene|1F56C126099E1D5241069E06477F277C12B20C58|yveG]-[gene|ECA64CB1E4BF8B6B0854B1B63C9E85A519059C6C|padC]
    description
    [Pubmed|18326577]

    regulatory mechanism

  • [protein|A7824EACE0C109C676A374FD21F59D671B703305|PadR]: repression, [Pubmed|18326577], in [regulon|A7824EACE0C109C676A374FD21F59D671B703305|PadR regulon]

    • regulation

  • induced by phenolic acid ([protein|search|PadR]) [Pubmed|18326577]
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    Biological materials

    Mutant

  • BKE34400 (Δ[gene|ECA64CB1E4BF8B6B0854B1B63C9E85A519059C6C|padC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE34400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTTACACACTCTCCTTA, downstream forward: _UP4_TAATAAACATAAAAACCCGG
  • BKK34400 (Δ[gene|ECA64CB1E4BF8B6B0854B1B63C9E85A519059C6C|padC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK34400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTTACACACTCTCCTTA, downstream forward: _UP4_TAATAAACATAAAAACCCGG

    • References

  • 18326577,17295427,9546183,21685295,26408050,23081771,21045284,26190963,26658822