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fhuG [Mon Aug 31 2015 13:56:46 GMT+0200 (CEST)]
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fhuG [Mon Aug 31 2015 13:56:46 GMT+0200 (CEST)]

hydroxamate siderophore ABC transporter (ferrichrome und ferrioxamine) (permease)
locus
BSU33300
pI
10.20
mw
36.00 kDa
function
siderophore uptake
product
hydroxamate siderophore ABC transporter
(ferrichrome und ferrioxamine) (permease)
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.5|Uptake of iron/ siderophores]
  • [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.3|Acquisition of iron] → [category|SW 1.3.3.1|ABC transporters for the uptake of iron/ siderophores]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.4|ABC transporters for the uptake of iron/ siderophores]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|ABC transporters], [SW|acquisition of iron], [SW|iron metabolism], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|Fur regulon]
  • The protein

    Protein family

  • FecCD subfamily (according to Swiss-Prot)
  • Structure

  • [PDB|4R9U], the ''E. coli'' BtuC-BtuD complex, BtuC shares 33% identity, 67% similarity with FhuG, [Pubmed|25402482]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|FhuC]-([protein|search|FhuB]-[protein|search|FhuG])-([protein|search|FhuD]-[protein|search|YxeB]) [Pubmed|10092453]
  • Expression and Regulation

    Regulation

  • induced upon iron starvation ([protein|search|Fur]) [Pubmed|12354229]
  • Regulatory mechanism

  • [protein|search|Fur]: transcription repression [Pubmed|12354229]
  • References

  • 10092453,16672620,25402482,12354229