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21st International Conference on Bacilli and Gram-Positive Bacteria. Prague, Czech Republic, June 7-11, 2021.
rpsO [Mon Oct 10 2016 19:50:54 GMT+0200 (CEST)]
ribosomal protein S15 (BS18)
categories[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 22.214.171.124|Ribosomal proteins][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
[SW|Categories] containing this gene/protein[SW|translation], [SW|essential genes]
This gene is a member of the following [SW|regulons][SW|stringent response]
Coordinates on the chromosome (coding sequence)
1,738,941 -> 1,739,210
Phenotypes of a mutantessential [Pubmed|23002217,12682299]
Protein family[SW|ribosomal protein] S15P family (according to Swiss-Prot)
Structure[PDB|1A32] (''Geobacillus stearothermophilus'')[PDB|3J9W] (the [SW|ribosome]) [Pubmed|25903689]
[SW|Interactions][SW|23S rRNA]-[rpsO|search|S15] [Pubmed|10497132][SW|16S rRNA]-[rpsO|search|S15] [Pubmed|11846555]
Expression and Regulation
Regulation[protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]translational repression of ''rpsO'' expression upon binding of excess [protein|search|RpsO] to a [SW|RNA switch] in the untranslated region of the ''rpsO'' mRNA [Pubmed|23611891,16005889]
Additional informationthe mRNA is processed, this is initiated by [rny|search|RNase Y] and cleavage products are subsequently subject to exonucleolytic degradation by RNases [rnjA|search|J1] and [rnjB|search|J2] and by [pnpA|search|PNPase] [PubMed|20418391]