product
ribosomal protein S15 (BS18)
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.1|Translation] → [category|SW 3.3.1.4|Ribosomal proteins][category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes][SW|Categories] containing this gene/protein
[SW|translation], [SW|essential genes]This gene is a member of the following [SW|regulons]
[SW|stringent response]Gene
Coordinates on the chromosome (coding sequence)
1,738,941 -> 1,739,210
Phenotypes of a mutant
essential [Pubmed|23002217,12682299]The protein
Protein family
[SW|ribosomal protein] S15P family (according to Swiss-Prot)Structure
[PDB|1A32] (''Geobacillus stearothermophilus'')[PDB|3J9W] (the [SW|ribosome]) [Pubmed|25903689][SW|Interactions]
[SW|23S rRNA]-[rpsO|search|S15] [Pubmed|10497132][SW|16S rRNA]-[rpsO|search|S15] [Pubmed|11846555]Expression and Regulation
Operon
''rpsO'' [Pubmed|19633085]Regulation
[protein|search|RelA] dependent downregulation (Class I) during stringent response [Pubmed|11948165]translational repression of ''rpsO'' expression upon binding of excess [protein|search|RpsO] to a [SW|RNA switch] in the untranslated region of the ''rpsO'' mRNA [Pubmed|23611891,16005889]Additional information
the mRNA is processed, this is initiated by [rny|search|RNase Y] and cleavage products are subsequently subject to exonucleolytic degradation by RNases [rnjA|search|J1] and [rnjB|search|J2] and by [pnpA|search|PNPase] [PubMed|20418391]References
19633085,19653700,20418391,10497132,11846555,23002217,16005889,23611891,25903689 
