SubtiBank SubtiBank
ffh
An ordered knock out library of all non-essential genes in B. subtilis is now available at Addgene. Information on ordering a copy can be found here. See Koo et al. 2017 for details about library construction.

ffh

signal recognition particle (SRP) component
locus
BSU15980
pI
9.42
mw
49.38 kDa
protein length
446 aa Sequence Blast
gene length
1338 bp Sequence Blast
function
presecretory protein translocation
product
signal recognition particle (SRP) component
essential
yes
synonyms

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • Gene

    Coordinates
    1,672,174 → 1,673,514

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Protein family

  • GTP-binding [protein|search|SRP] family (according to Swiss-Prot)
  • Structure

  • [PDB|4UE4] (complex [protein|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|Ffh]-[protein|097C817A5A3E31F73F6ABC4AA95852A64E43A057|Scr] RNA) [Pubmed|26344568]
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operons

    genes
    [gene|8F559BFC80FE56EA0389A2336F4E9E6908562BCB|ylxM]-[gene|EC025F78D0BCBD91162BAAB9EAB7D3837E0A3208|ffh]
    description
    [Pubmed|8335643]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|8335643], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
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    References

    Reviews

  • 25212246,27890920
  • Original publications

  • 16705751,9346318,9880811,8335643,21330537,23563142,24659773,26344568