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snaB [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]
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snaB [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

sulphur N-acetylase, the yxeK-snaB-yxeM-yxeN-yxeO-sndB-yxeQ operon may be implicated in the utilization of a modified cysteine variant
locus
BSU39510
pI
9.13
mw
18.00 kDa
function
unknown
product
sulphur N-acetylase
essential
no
synonyms
yxeL

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.4|Sulfur metabolism] → [category|SW 2.6.4.3|Conversion of S-(2-succino)cysteine to cysteine]
  • [category|SW 2|Metabolism] → [category|SW 2.7|Detoxification reactions]
  • [SW|Categories] containing this gene/protein

  • [SW|poorly characterized/ putative enzymes]
  • This gene is a member of the following [SW|regulons]

  • [SW|CymR regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    4,060,307 -> 4,060,804

    Phenotypes of a mutant

  • the ''[protein|search|snaA] [protein|search|snaB]'' double mutant does not grow with S-methyl cysteine [Pubmed|23944997]
  • The protein

    Protein family

  • acetyltransferase family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|search|SnaA]
  • Expression and Regulation

    Operon

  • ''[protein|search|yxeK]-[protein|search|snaB]-[protein|search|yxeM]-[protein|search|yxeN]-[protein|search|yxeO]-[protein|search|sndB]-[protein|search|yxeQ]'' [Pubmed|10746760]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|16513748]
  • Regulation

  • repressed in the presence of cysteine ([protein|search|CymR]) [Pubmed|16513748]
  • Regulatory mechanism

  • [protein|search|CymR]: transcription repression [Pubmed|16513748]
  • Additional information

  • the amount of the mRNA is substantially decreased upon depletion of [Rny|search|RNase Y] [PubMed|21815947]
  • References

  • 10746760,15937167,16513748,21815947,23944997