flagellar basal-body M-ring protein, membrane anchor of the basal body
function
movement and chemotaxis
product
flagellar basal-body M-ring protein
Genomic Context
categories
[category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.2|Flagellar proteins][category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.2|Biofilm formation] → [category|SW 4.1.2.6|Other proteins required for efficient pellicle biofilm formation][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|motility and chemotaxis], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|CodY regulon], [SW|DegU regulon], [SW|SigD regulon], [SW|Spo0A regulon]Gene
Coordinates on the chromosome (coding sequence)
1,692,496 -> 1,694,106
Phenotypes of a mutant
mucoid phenotype due to the overproduction of poly-gamma-glutamate [Pubmed|24296669]no secretion of [protein|search|FlgM], permanent inhibition of [protein|search|SigD] [Pubmed|25313396]not essential for pellicle biofilm formation, but mutant is outcompeted by the wild-type strain when competed during pellicle formation [Pubmed|26122431]The protein
Catalyzed reaction/ biological activity
required for correct localization of [protein|search|FliM] [Pubmed|23190039]Protein family
fliF family (according to Swiss-Prot)[SW|Localization]
cell membrane [Pubmed|18763711][SW|Interactions]
[protein|search|FliF]-[protein|search|FliG] [Pubmed|25313396]Expression and Regulation
Operon
part of the [[fla-che operon]] (see there for regulation)''[protein|search|flgB]-[protein|search|flgC]-[protein|search|fliE]-[protein|search|fliF]-[protein|search|fliG]-[protein|search|fliH]-[protein|search|fliI]-[protein|search|fliJ]-[protein|search|ylxF]-[protein|search|fliK]-[protein|search|flgD]-[protein|search|flgE]-[protein|search|fliL]-[protein|search|fliM]-[protein|search|fliY]-[protein|search|cheY]-[protein|search|fliZ]-[protein|search|fliP]-[protein|search|fliQ]-[protein|search|fliR]-[protein|search|flhB]-[protein|search|flhA]-[protein|search|flhF]-[protein|search|flhG]-[protein|search|cheB]-[protein|search|cheA]-[protein|search|cheW]-[protein|search|cheC]-[protein|search|cheD]-[protein|search|sigD]-[protein|search|swrB]'' [Pubmed|9657996,8157612,15175317][SW|Sigma factor]
[protein|search|SigA] [Pubmed|9657996], [protein|search|SigD] [Pubmed|9657996]Regulation
see [[fla-che operon]]Regulatory mechanism
see [[fla-che operon]]Biological materials
Mutant
DS7080 (marker-less in NCIB3610) [Pubmed|24296669]References
26122431,1905667,17850253,14651647,18763711,9657996,8157612,15175317,23190039,24296669,25313396,24386445,25843804 
