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spoVG [Tue Dec 13 2016 11:16:29 GMT+0100 (CET)]
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spoVG [Tue Dec 13 2016 11:16:29 GMT+0100 (CET)]

RNA-binding regulatory protein, negative effector of asymetric septation at the onset of sporulation
locus
BSU00490
pI
5.00
mw
10.00 kDa
function
cell division, control of sporulation initiation
product
negative effector of asymetric septation
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes]
  • [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.2|RNA chaperones]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.3|Sporulation/ other]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]
  • [SW|Categories] containing this gene/protein

  • [SW|cell division], [SW|sporulation/ other], [SW|phosphoproteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon], [SW|SigH regulon], [SW|SinR regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    55,866 -> 56,159

    The protein

    Protein family

  • spoVG family (according to Swiss-Prot)
  • Modification

  • phosphorylation on (Ser-66 OR Ser-67 OR Thr-68) [Pubmed|17218307]
  • Structure

  • [PDB|2IA9]
  • Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation [PubMed|17981983]
  • Expression and Regulation

    Operon

  • ''spoVG'' [Pubmed|408013]
  • [SW|Sigma factor]

  • [protein|search|SigH] [Pubmed|408013]
  • Regulation

  • repressed by [protein|search|SinR] [Pubmed|16430695]
  • repressed during logrithmic growth ([protein|search|AbrB]) [Pubmed|2437099]
  • Regulatory mechanism

  • [protein|search|SinR]: transcription repression [Pubmed|16430695]
  • [protein|search|AbrB]: transcription repression [Pubmed|2437099]
  • Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation [PubMed|17981983]
  • Biological materials

    Mutant

  • GP2109 (''[protein|search|spoVG]''::''tet'', available in [SW|Jörg Stülke]'s lab)
  • References

  • 408013,1850083,16430695,6405278,6411929,10348850,7559352,8419299,3100810,2437099,17218307,20803133,27048798