ywrO

similar to NAD(P)H oxidoreductase

locus: BSU_35990

pI: 5.20

mw: 19.81 kDa

protein length: 175 aa

gene length: 528 bp

function: unknown

product: unknown

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.4|Electron transport/ other/ based on similarity]

Gene

Coordinates: 3,708,172 → 3,708,699

The protein

Protein family

• NAD(P)H dehydrogenase (quinone) family (with [protein|2782BD764716CF5FAD0988284310CF75508F2286|YdeQ] and [protein|2EA9792C1C7CD89E43742F57FFB7300725B6AEF4|YrkL], according to UniProt)

Paralogous protein(s)

• [protein|2782BD764716CF5FAD0988284310CF75508F2286|YdeQ], [protein|2EA9792C1C7CD89E43742F57FFB7300725B6AEF4|YrkL]

[SW|Cofactors]

• FMN or FAD [Pubmed|21635694]

Structure

• [PDB|5LVA] (from Streptomyces violaceus, 55% identity) [pubmed|27714222]

Expression and Regulation

Operons

• genes: [gene|E8048E181756BCE307CF28CF31664421404748A4|ywrO]
  description: [Pubmed|9353933]

Biological materials

Mutant

• MGNA-B652 (ywrO::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1651 NBRP B. subtilis, Japan]
• BKE35990 (Δ[gene|E8048E181756BCE307CF28CF31664421404748A4|ywrO]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE35990 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAGACCACACCTTTACT, downstream forward: _UP4_TAAAATACAGCCCTGTCCAA
• BKK35990 (Δ[gene|E8048E181756BCE307CF28CF31664421404748A4|ywrO]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK35990 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCAGACCACACCTTTACT, downstream forward: _UP4_TAAAATACAGCCCTGTCCAA

References

• 9353933,27714222