SubtiBank SubtiBank
sigX [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]
Save the date! 20th International Conference on Bacilli and Gram-Positive Bacteria. Washington, D.C. July 23-26, 2019.

sigX [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

RNA polymerase ECF-type sigma factor SigX, required for resistance against cationic antimicrobial peptides
locus
BSU23100
pI
6.00
mw
23.00 kDa
function
resistance to cationic antimcrobial peptides
product
RNA polymerase ECF-type sigma factor SigX
essential
no
synonyms
ypuM

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.2|Sigma factors]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.1|Sigma factors]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|transcription], [SW|sigma factors and their control], [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigX regulon], [SW|YvrHb regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,414,627 -> 2,415,211

    The protein

    Protein family

  • ECF subfamily (according to Swiss-Prot)
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|RsiX]-[protein|search|SigX] [Pubmed|9393439]
  • [protein|search|SigX]-[protein|search|RpoB]-[protein|search|RpoC]
  • Additional information

  • Expression of the [SW|SigX regulon] in increased in ''[protein|search|ugtP]'' mutants [Pubmed|22362028]
  • Expression and Regulation

    Operon

  • ''[protein|search|sigX]-[protein|search|rsiX]'' [Pubmed|7934830]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|9636707], [protein|search|SigX] [Pubmed|9636707]
  • Regulation

  • induced in the stationary phase due to the internal production of toxic peptides ([SW|SdpC], [SW|SkfA]) [Pubmed|26364265]
  • Regulatory mechanism

  • activated by [SW|YvrHb] [Pubmed|16306698]
  • Biological materials

    Mutant

  • 1A901 ( ''sigX''::''spec''), [Pubmed| ], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A901&Search=1A901 BGSC]
  • References

    Reviews

  • 24921931,26901131
  • The [SW|SigX regulon]

  • 9683469,17675383,10960106
  • Other original publications

  • 11222589,9139908,14993308,12399481,14762009,19047346,14651641,19465659,9636707,16306698,7934830,19767430,9393439,22362028,23103977,20817771,26364265,27137497