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yweA [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]
inhibitor of KinA autophosphorylation, and subsequently of entry into sporulation
function
control of entry into sporulation via the phosphorelay
product
inhibitor of KinA autophosphorylation
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.7|phosphorelay] → [category|SW 3.4.7.2|Proteins controlling the activity of the kinases][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.2|phosphorelay] → [category|SW 4.2.2.2|Proteins controlling the activity of the kinases][category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins][SW|Categories] containing this gene/protein
[SW|phosphorelay]This gene is a member of the following [SW|regulons]
[SW|AbrB regulon]Gene
Coordinates on the chromosome (coding sequence)
3,882,191 -> 3,882,655
Phenotypes of a mutant
the'' [protein|search|sivA] [protein|search|bslA]'' double mutant exhibits a more severe loss of repellency of the biofilm surface as compared to the ''[protein|search|bslA]'' mutant [Pubmed|22571672]The protein
Catalyzed reaction/ biological activity
inhibits [protein|search|KinA] autophophorylation [Pubmed|23335417]Paralogous protein(s)
[protein|search|BslA][SW|Localization]
membrane (according to Swiss-Prot)extracellular (signal peptide) [Pubmed|18957862]Expression and Regulation
Operon
''sivA'' [Pubmed|12823818]Regulatory mechanism
[protein|search|AbrB]: transcription repression [Pubmed|20817675]References
18957862,12823818,22571672,23335417,20817675