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yqhB [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]
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yqhB [Thu Oct 01 2015 13:51:44 GMT+0200 (CEST)]

general stress protein, required for protection against oxidative stress
locus
BSU24750
pI
5.00
mw
49.00 kDa
function
protection against stress conditions
product
unknown
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.1|Metal ion homeostasis (K, Na, Ca, Mg)] → [category|SW 1.3.1.1|Magnesium uptake/ efflux]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|general stress proteins (controlled by SigB)], [SW|resistance against oxidative and electrophile stress], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|LexA regulon], [SW|SigB regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,561,585 -> 2,562,913

    The protein

    Protein family

  • UPF0053 family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [SW|YhdP], [SW|YhdT], [SW|YrkA], [SW|YugS]
  • [SW|Domains]

  • [SW|DUF21 domain] (14-210)
  • 2 [SW|CBS domain]s (229-290, 295-355)
  • [SW|Localization]

  • cell membrane (according to Swiss-Prot)
  • Expression and Regulation

    Operon

  • ''yqhB'' [Pubmed|16267290]
  • [SW|Sigma factor]

  • [protein|search|SigB] [Pubmed|15805528]
  • Regulation

  • induced by stress ([protein|search|SigB]) [Pubmed|15805528]
  • induced upon DNA damage ([protein|search|LexA]) [Pubmed|16267290]
  • Regulatory mechanism

  • [protein|search|LexA]: transcription repression [Pubmed|16267290]
  • Biological materials

    Expression vector

  • pGP2935 (N-terminal His-tag, purification from ''E. coli'', in [SW|pWH844]), available in [SW|Jörg Stülke]'s lab
  • References

  • 16267290,15805528,22582280