general stress protein, required for protection against oxidative stress
function
protection against stress conditions
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.1|Metal ion homeostasis (K, Na, Ca, Mg)] → [category|SW 1.3.1.1|Magnesium uptake/ efflux][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|general stress proteins (controlled by SigB)], [SW|resistance against oxidative and electrophile stress], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|LexA regulon], [SW|SigB regulon]Gene
Coordinates on the chromosome (coding sequence)
2,561,585 -> 2,562,913
The protein
Protein family
UPF0053 family (according to Swiss-Prot)Paralogous protein(s)
[SW|YhdP], [SW|YhdT], [SW|YrkA], [SW|YugS][SW|Domains]
[SW|DUF21 domain] (14-210)2 [SW|CBS domain]s (229-290, 295-355)[SW|Localization]
cell membrane (according to Swiss-Prot)Expression and Regulation
Operon
''yqhB'' [Pubmed|16267290][SW|Sigma factor]
[protein|search|SigB] [Pubmed|15805528]Regulation
induced by stress ([protein|search|SigB]) [Pubmed|15805528]induced upon DNA damage ([protein|search|LexA]) [Pubmed|16267290]Regulatory mechanism
[protein|search|LexA]: transcription repression [Pubmed|16267290]Biological materials
Mutant
MGNA-C474 (yqhB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2472 NBRP B. subtilis, Japan]Expression vector
pGP2935 (N-terminal His-tag, purification from ''E. coli'', in [SW|pWH844]), available in [SW|Jörg Stülke]'s labReferences
16267290,15805528,22582280 
