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mcpB [2017-8-11 16:0:3]
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mcpB [2017-8-11 16:0:3]

membrane-bound chemotaxis receptor, methyl-accepting chemotaxis protein, receptor for asparagine
locus
BSU31260
pI
5.13
mw
71.70 kDa
protein length
662 aa Sequence Blast
gene length
1986 bp Sequence Blast
function
control of chemotaxis
product
methyl-accepting chemotaxis protein
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.1|Signal transduction in motility and chemotaxis] → [category|SW 4.1.1.1.4|Membrane-bound chemoreceptors]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • Gene

    Coordinates
    3,210,445 → 3,212,433

    The protein

    Paralogous protein(s)

  • [protein|F02E3080214A327E131ECDE0DBC52C57EFDFE2CE|McpA]
  • Kinetic information

  • K(D) for asparagine: 14 myM [Pubmed|19864420]
  • Modification

  • methylated at residues Gln371, Glu630, and Glu637 [Pubmed|20864474]
  • Effectors of protein activity

  • asparagine (binds to the part of McpB that is exposed to the exterior) [Pubmed|19864420]
  • [SW|Localization]

  • cell membrane [Pubmed|18763711,21515776]
  • localized at the cell poles, but in the presence of high asparagine concentration there is a reversible re-localization to the sides of the cell (lateral clusters) [Pubmed|21098025]
  • Expression and Regulation

    Operons

    genes
    [gene|E4E1020B799A1B403BDB4847B91B02D64D161AF3|mcpB]
    description
    [Pubmed|8188684]

    sigma factors

  • [protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD]: sigma factor, [Pubmed|8188684], in [regulon|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD regulon]
  • additional information

  • in minimal medium, McpB is present with 6,200 /- 1,900 molecules per cell [PubMed|21515776]
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    References

  • 11722727,10825179,8251536,12909020,10196193,15544802,6137212,9194713,2505839,8188684,2105313,12123464,14731274,20864474,18763711,19864420,21098025,21515776,25039821,27899502