yerA [2019-03-21 10:48:15]

similar to adenine desaminase

locus: BSU06560

pI: 5.82

mw: 66.47 kDa

protein length: 580 aa

gene length: 1743 bp

function: unknown

product: unknown

essential: no

ec: 3.5.4.2

synonyms

Genomic Context

categories

• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]
• [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.5|Phosphorylation on a Ser residue]
• [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

Gene

Coordinates: 713,664 → 715,406

The protein

Catalyzed reaction/ biological activity

• Adenine + H₂O = hypoxanthine + NH₃ (according to Swiss-Prot)

Protein family

• adenine deaminase family (according to Swiss-Prot)

Modification

• phosphorylation on Ser-399 [Pubmed|17218307]

Expression and Regulation

Operons

• genes: [gene|E20A5429BCD8719A403229AFB200225EA14EE2DB|yerA]-[gene|BE1F7BA77CE8B6A1A2D22F31421C27F2E954816A|yerB]-[gene|B948BD67148DC53B371E6748347982067CE28C36|yerC]
  description: [pubmed|22383849]

Biological materials

Mutant

• MGNA-A910 (yerA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/910 NBRP B. subtilis, Japan]
• BKE06560 (Δ[gene|E20A5429BCD8719A403229AFB200225EA14EE2DB|yerA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE06560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCACATACTCTCCTTTA, downstream forward: _UP4_TAAAATATAAAAGAGCAGGG
• BKK06560 (Δ[gene|E20A5429BCD8719A403229AFB200225EA14EE2DB|yerA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK06560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCACATACTCTCCTTTA, downstream forward: _UP4_TAAAATATAAAAGAGCAGGG

References

• 17218307