SubtiBank SubtiBank
rapB
Save the date! 20th International Conference on Bacilli and Gram-Positive Bacteria. Washington, D.C. July 23-26, 2019.

rapB

response regulator aspartate phosphatase, dephosphorylates Spo0F-P, control of the phosphorelay
locus
BSU_36690
pI
4.87
mw
44.88 kDa
protein length
377 aa Sequence Blast
gene length
1134 bp Sequence Blast
function
control of sporulation initiation
product
response regulator aspartate phosphatase
essential
no
synonyms
spo0P,ywmE

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.4|Protein modification] → [category|SW 3.3.4.4|Protein phosphatases]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.2|Control of two-component response regulators] → [category|SW 3.4.2.2.2|Response regulator aspartate phosphatase]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.7|phosphorelay] → [category|SW 3.4.7.5|Phosphatases controlling the phosphorelay]
  • [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.2|phosphorelay] → [category|SW 4.2.2.5|Phosphatases controlling the phosphorelay]
  • Gene

    Coordinates
    3,771,000 → 3,772,133

    The protein

    Protein family

  • [SW|RAP family] (according to UniProt)
  • [SW|Domains]

  • six [SW|TPR repeat|tetratrichopeptide repeats] (according to UniProt)
  • Structure

  • [PDB|4I9E] ([protein|1F860F4E66A3D503D5A97F17D4AB0504BEFE7F9D|RapF], 43% identity) [pubmed|23526880]
  • Expression and Regulation

    Operons

    genes
    [gene|E07E123CC9FB3B29DDA8EC58A33FEEE1DDFC4834|rapB]
    description
    [Pubmed|9353933]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|11535782], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • view in new tab

    Biological materials

    Mutant

  • BKE36690 (Δ[gene|E07E123CC9FB3B29DDA8EC58A33FEEE1DDFC4834|rapB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE36690 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCCCCTCCAACCCTTTC, downstream forward: _UP4_TGAGACAAAACCATCTGCTG
  • BKK36690 (Δ[gene|E07E123CC9FB3B29DDA8EC58A33FEEE1DDFC4834|rapB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK36690 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGCCCCTCCAACCCTTTC, downstream forward: _UP4_TGAGACAAAACCATCTGCTG
  • References

  • 8643670,8730857,12067336,9843420,11535782,23526880