ytbE

putative aldo/keto reductase, may be involved in detoxification

locus: BSU_29050

pI: 4.79

mw: 31.62 kDa

protein length: 280 aa

gene length: 843 bp

function: unknown

product: putative aldo/keto reductase

essential: no

ec: 1.-.-.-

synonyms

Genomic Context

categories

• [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

Gene

Coordinates: 2,970,038 → 2,970,880

Phenotypes of a mutant

• essential [Pubmed|17114254], non-essential according to [Pubmed|28189581]

The protein

Protein family

• [SW|Nudix hydrolase]
• [SW|Aldo/keto reductase family] (according to UniProt)

Paralogous protein(s)

• [protein|994D5A36AECC75F5D0B59F7755BC5DB935ED6CE8|YvgN]

Structure

• [PDB|3B3D] [Pubmed|19585557]

Expression and Regulation

Operons

• genes: [gene|BADE5937ECB41C96C82E6A3BDA8FDC9BFC21F219|ytbD]-[gene|DE12190315DADF13DA1BA272924729BBF909B1D9|ytbE]
  description: [pubmed|22383849]

Biological materials

Mutant

• MGNA-A119 (ytbE::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/119 NBRP B. subtilis, Japan]
• BKE29050 (Δ[gene|DE12190315DADF13DA1BA272924729BBF909B1D9|ytbE]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE29050 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTTATTTCCTCCTTTA, downstream forward: _UP4_TAATGGCCAAAAAACACCGT
• BKK29050 (Δ[gene|DE12190315DADF13DA1BA272924729BBF909B1D9|ytbE]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK29050 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTTTATTTCCTCCTTTA, downstream forward: _UP4_TAATGGCCAAAAAACACCGT

References

• 17114254,19585557,28189581