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menH [Tue May 03 2016 10:21:53 GMT+0200 (CEST)]
menaquinone biosynthesis methyltransferase
function
biosynthesis of menaquinone
product
menaquinone biosynthesis methyltransferase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.8|Biosynthesis of menaquinone][category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.2|Biofilm formation] → [category|SW 4.1.2.5|Other proteins required for biofilm formation][SW|Categories] containing this gene/protein
[SW|biosynthesis of cofactors], [SW|sporulation/ other]Gene
Coordinates on the chromosome (coding sequence)
2,382,907 -> 2,383,608
Phenotypes of a mutant
essential [http://www.ncbi.nlm.nih.gov/pubmed/?term=12682299 according to Kobayashi et al. ]; however, inactivation reported by [http://www.ncbi.nlm.nih.gov/pubmed/?term=26735940 Meeske et al. ]inactivation of ''[SW|menH]'' reduces sporulation efficiency to 12.7% that of wild type cells [Pubmed|26735940]The protein
Catalyzed reaction/ biological activity
S-adenosyl-L-methionine demethylmenaquinol = s-adenosyl-L-homocysteine menaquinol (according to Swiss-Prot) Structure
[PDB|1OBW] (from ''Saccharomyces cerevisiae'', 31% identity) [Pubmed|9201917]References
