SubtiBank SubtiBank
appA/1
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appA/1

oligopeptide ABC transporter, inactive pseudogene in strain 168
locus
BSU_11381
pI
0.00
mw
0.00 kDa
protein length
154 aa Sequence Blast
gene length
465 bp Sequence Blast
function
unknown
product
oligopeptide ABC transporter
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.1|Importers] → [category|SW 1.2.1.1.3|Uptake of peptides]
  • [category|SW 6|Groups of genes] → [category|SW 6.10|Pseudogenes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • Gene

    Coordinates
    1,213,537 → 1,214,001

    The protein

    Protein family

  • [SW|bacterial solute-binding protein 5 family] (according to UniProt)
  • Structure

  • [PDB|1XOC] (the intact protein) [pubmed|15588833]
  • [SW|Localization]

  • attached to the cell membrane (via [protein|C6EB94EACDA544700A468545BD1FDA91C5FD82FB|AppB]-[protein|252E3F0A05D78CEC46A08B46D1C6133239B6B8BA|AppC]) [Pubmed|10092453]
  • Expression and Regulation

    Operons

    genes
    [gene|325BCDCAB4003204294229B7F9F0A5F353D72B54|appD]-[gene|B88A88B4792FFFF4E1609B1FC91AAE6DBA339044|appF]-[gene|DD2C5F549759447FF1C30E5B43BCB74CE4320EF3|appA/1]-[gene|082D2012ABE3671F62211F77ED501849BF77B4EF|appA/2]-[gene|C6EB94EACDA544700A468545BD1FDA91C5FD82FB|appB]-[gene|252E3F0A05D78CEC46A08B46D1C6133239B6B8BA|appC]
    description
    [Pubmed|7997159]

    regulatory mechanism

  • [protein|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA]: activation, [Pubmed|25755103], in [regulon|857EF1AC54DEA0690C01B7F8CEFFD16312C58F20|TnrA regulon]
  • [protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY]: repression, [pubmed|12618455] [pubmed|18083814], in [regulon|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY regulon]
  • [protein|F7FD94CE7AB290FBFD3A9B88F204961668F9B42C|ScoC]: repression, [Pubmed|10383984], in [regulon|F7FD94CE7AB290FBFD3A9B88F204961668F9B42C|ScoC regulon]
  • regulation

  • repressed by [protein|90ACE0DECA58D3C1A55E135120F7A0C1C920571C|CodY] [Pubmed|12618455]
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    Biological materials

    Mutant

  • GP2100 (D(''[gene|325BCDCAB4003204294229B7F9F0A5F353D72B54|appD]-[gene|B88A88B4792FFFF4E1609B1FC91AAE6DBA339044|appF]-[gene|082D2012ABE3671F62211F77ED501849BF77B4EF|appA/2]-[gene|C6EB94EACDA544700A468545BD1FDA91C5FD82FB|appB]-[gene|252E3F0A05D78CEC46A08B46D1C6133239B6B8BA|appC]'')::''spc''), available in [SW|Jörg Stülke]'s lab
  • BKE11381 (Δ[gene|DD2C5F549759447FF1C30E5B43BCB74CE4320EF3|appA/1]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE11381 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTAGATATTCCCCCTCTT, downstream forward: _UP4_ATGCTGAAATCCGTAGAAAA
  • BKK11381 (Δ[gene|DD2C5F549759447FF1C30E5B43BCB74CE4320EF3|appA/1]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK11381 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTAGATATTCCCCCTCTT, downstream forward: _UP4_ATGCTGAAATCCGTAGAAAA
  • References

  • 12618455,7997159,10092453,10383984,12618455,25755103,15588833