secreted quality control protease
function
protein quality control
product
secreted quality control protease
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.5|Cell wall/ other][category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.1|Protein quality control][category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins][SW|Categories] containing this gene/protein
[SW|cell wall/ other], [SW|proteolysis]This gene is a member of the following [SW|regulons]
[SW|YvrHb regulon], [SW|CcpA regulon]The protein
Catalyzed reaction/ biological activity
important for [SW|TatAY]-[SW|TatCY]-dependent export of [protein|search|YkuE] and [protein|search|YwbN] [Pubmed|23180473]involved in degradation of [protein|search|PrsA], [protein|search|HtrA], and [protein|search|HtrB] [Pubmed|24362423]Protein family
peptidase S8 family (according to Swiss-Prot)[SW|Localization]
extracellular (signal peptide) [Pubmed|18957862]membrane [Pubmed|18763711]cell wall [Pubmed|23180473][SW|Interactions]
[protein|search|WprA]-[SW|TatAY] [Pubmed|23180473][protein|search|WprA]-[SW|TatCY] [Pubmed|23180473]Expression and Regulation
Operon
''[protein|search|wprA]'' [Pubmed|16306698][SW|Sigma factor]
[protein|search|SigA] [Pubmed|22900538]Regulation
repressed by glucose ([protein|search|CcpA]) [Pubmed|22900538]Regulatory mechanism
[protein|search|CcpA]: transcription repression [Pubmed|22900538][SW|YvrHb]: transcription activation [Pubmed|16306698]Biological materials
Mutant
1A1021 ( ''wprA''::''kan''), [Pubmed|20400548], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A1021&Search=1A1021 BGSC]References
Reviews
Original publications
22900538,22923395,23180473,21815947,10075409,11987133,9004506,20525796,18957862,18763711,16306698,9687444,12028417,24362423,24115457