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ganA [Mon Feb 29 2016 16:32:19 GMT+0100 (CET)]
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ganA [Mon Feb 29 2016 16:32:19 GMT+0100 (CET)]

beta-galactosidase
locus
BSU34130
pI
5.00
mw
79.00 kDa
function
galactan utilization
product
beta-galactosidase
essential
no
ec
3.2.1.23
synonyms
yvfN, lacA

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.24|Utilization of galactan]
  • [category|SW 6|Groups of genes] → [category|SW 6.4|Phosphoproteins] → [category|SW 6.4.1|Phosphorylation on an Arg residue]
  • [SW|Categories] containing this gene/protein

  • [SW|utilization of specific carbon sources], [SW|phosphoproteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|LacR regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,503,020 -> 3,505,083

    Phenotypes of a mutant

  • a ''[protein|search|cycB]-[protein|search|ganP]-[protein|search|ganQ]-[protein|search|ganA]-[protein|search|ganB]'' mutant is impaired in the utilization of galactan [Pubmed|22893383]
  • The protein

    Catalyzed reaction/ biological activity

  • degradation of galactotriose to galactose [Pubmed|22893383]
  • Protein family

  • glycosyl hydrolase 42 family (according to Swiss-Prot)
  • Modification

  • phosphorylated on Arg-387 [Pubmed|22517742]
  • Expression and Regulation

    Operon

  • ''[protein|search|cycB]-[protein|search|ganP]-[protein|search|ganQ]-[protein|search|ganA]-[protein|search|ganB]'' [Pubmed|9287030]
  • Regulatory mechanism

  • [protein|search|LacR]: transcription repression [Pubmed|9287030]
  • Biological materials

    Mutant

  • GP1181 (aphA3) available in the [SW|Stülke] lab
  • 1A785 ( ''ganA''::''spec''), [Pubmed|11274134], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A785&Search=1A785 BGSC]
  • 1A786 ( ''ganA''::''spec''), [Pubmed|11274134], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A786&Search=1A786 BGSC]
  • References

  • 2104611,9287030,17056685,22517742,22893383