serine protease, cleaves SpoIVFA to prepare it for CtpB cleavage, this results in pro-SigK processing/activation in the mother-cell, does also cleave CtpB
function
control of SigK activation
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][SW|Categories] containing this gene/protein
[SW|sigma factors and their control], [SW|sporulation proteins]This gene is a member of the following [SW|regulons]
[SW|SigF regulon], [SW|SigG regulon]The protein
Catalyzed reaction/ biological activity
Self-cleaves 52-Val-|-Asn-53, 62-Ala-|-Phe-63 and 74-Val-|-Thr-75 at the N-terminus of SpoIVB (according to Swiss-Prot)Protein family
PDZ protease [Pubmed|24243021][SW|Localization]
intracellular space between the mother cell and the forespore [Pubmed|24243021][SW|Interactions]
[SW|SpoIVB]-[protein|search|BofA] [Pubmed|15292188][protein|search|BofC]-[SW|SpoIVB] [Pubmed|10931291][SW|SpoIVB]-[SW|SpoIVFA] [Pubmed|24243021]Expression and Regulation
Operon
''spoIVB'' [Pubmed|2106508][SW|Sigma factor]
[protein|search|SigF] [Pubmed|15699190,9004507], [protein|search|SigG] [Pubmed|15699190,9004507]Regulation
expressed during sporulation in the forespore ([protein|search|SigF], [protein|search|SigG], [SW|SpoVT]) [Pubmed|16497325,15699190,9004507,8755877]Regulatory mechanism
[SW|SpoVT]: transcription activation [Pubmed|8755877]Labs working on this gene/protein
Simon Cutting, London, UK [http://personal.rhul.ac.uk/uhba/009/bacillus/simon_cutting.html homepage]References
17493131,2106508,10931284,14526016,10931291,1900494,11418578,15292188,9004507,12940997,11741860,16497325,8755877,24243021,15292188,17557826,16818230 
