SubtiBank SubtiBank
yitW
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yitW

iron-sulphur cluster assembly factor
locus
BSU_11160
pI
4.10
mw
11.18 kDa
protein length
102 aa Sequence Blast
gene length
309 bp Sequence Blast
function
assembly of iron-sulphur clusters
product
iron-sulphur cluster assembly factor
essential
no
synonyms
sufT

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.5|Iron metabolism] → [category|SW 2.6.5.3|Biosynthesis of iron-sulfur clusters]
  • Gene

    Coordinates
    1,192,254 → 1,192,562

    The protein

    Protein family

  • MIP18 family (single member, according to UniProt)
  • [SW|Domains]

  • DUF59 [pubmed|28589301]
  • Structure

  • [PDB|3LNO] (from B. antracis, 58% identity)
  • Expression and Regulation

    Operons

    genes
    [gene|9592D944FE0863A3099E396D9A96F60E61D6C01C|yitV]-[gene|DB374B763EE496FA5F0904686384D94170CE47E3|yitW]
    description
    [Pubmed|22383849]
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    genes
    [gene|DB374B763EE496FA5F0904686384D94170CE47E3|yitW]
    description
    [Pubmed|22383849]
    view in new tab

    Biological materials

    Mutant

  • MGNA-A509 (yitW::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/509 NBRP B. subtilis, Japan]
  • BKE11160 (Δ[gene|DB374B763EE496FA5F0904686384D94170CE47E3|yitW]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE11160 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGTTCCCTCACTCCTTTT, downstream forward: _UP4_TAAAACAAAAAAGGACAGCC
  • BKK11160 (Δ[gene|DB374B763EE496FA5F0904686384D94170CE47E3|yitW]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK11160 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGTTCCCTCACTCCTTTT, downstream forward: _UP4_TAAAACAAAAAAGGACAGCC
  • References

    Reviews

  • 28589301
  • Research papers

  • 27517714,27671355