katX [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

catalase, general stress protein

locus: BSU38630

pI: 5.34

mw: 62.00 kDa

function: detoxification (degradation) of hydrogen peroxide

product: catalase (major catalase in spores)

essential: no

synonyms: yxlI

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]

[SW|Categories] containing this gene/protein

• [SW|sporulation proteins], [SW|general stress proteins (controlled by SigB)], [SW|resistance against oxidative and electrophile stress]

This gene is a member of the following [SW|regulons]

• [SW|RsfA regulon], [SW|SigB regulon], [SW|SigF regulon]

Gene

Coordinates on the chromosome (coding sequence): 3,964,997 -> 3,966,640

The protein

Catalyzed reaction/ biological activity

• 2 H₂O₂ = O₂ + 2 H₂O (according to Swiss-Prot)

Protein family

• catalase family (according to Swiss-Prot)

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operon

• ''katX'' [Pubmed|10503549]

[SW|Sigma factor]

• [protein|search|SigB] [Pubmed|10503549,15805528], [protein|search|SigF] [Pubmed|10503549,16497325]

Regulation

• expressed early during sporulation in the forespore ([protein|search|SigF], [protein|search|RsfA]) [Pubmed|16497325,15699190,10629188]
• induced by stress ([protein|search|SigB]) [Pubmed|10503549,15805528]

Regulatory mechanism

• [protein|search|RsfA]: transcription activation [Pubmed|10629188]

References

• 9393707,10503549,16497325,9555886,15805528,10629188