spoIIB

spatial and temporal regulation of the dissolution of septal peptidoglycan during engulfment

locus: BSU_28060

pI: 4.80

mw: 35.77 kDa

protein length: 332 aa

gene length: 999 bp

function: spore morphogenesis

product: facilitator of septal dissolution

essential: no

synonyms

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.3|Sporulation/ other]

Gene

Coordinates: 2,863,294 → 2,864,292

The protein

[SW|Domains]

• SPOR domain (aa 175-250) (according to UniProt)

[SW|Localization]

• cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

• genes: [gene|D98D61CA651AAA415386B1B2B41562E5CF77DEF1|spoIIB]
  description: [Pubmed|12107147]

  sigma factors

  • [protein|D04629D798E458AD538809BB2B150B7FA81D2C7E|SigV]: sigma factor, in [regulon|D04629D798E458AD538809BB2B150B7FA81D2C7E|SigV regulon]

  regulation

  • expression is reduced in a [protein|search|SigV] mutant [Pubmed|21926231]

Biological materials

Mutant

• BKE28060 (Δ[gene|D98D61CA651AAA415386B1B2B41562E5CF77DEF1|spoIIB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE28060 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTCCGCTTCCTCCCTTC, downstream forward: _UP4_TAAGAGATAGTGCCCTGAGC
• BKK28060 (Δ[gene|D98D61CA651AAA415386B1B2B41562E5CF77DEF1|spoIIB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK28060 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTCCGCTTCCTCCCTTC, downstream forward: _UP4_TAAGAGATAGTGCCCTGAGC

References

• 17376078,8419299,7559352,12107147