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tagO
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tagO

undecaprenyl-phosphate-GlcNAc-1-phosphate transferase, teichoic acid linkage unit synthesis
locus
BSU_35530
pI
10.42
mw
39.21 kDa
protein length
358 aa Sequence Blast
gene length
1077 bp Sequence Blast
function
biosynthesis of teichoic acid
product
undecaprenyl-phosphate-GlcNAc-1-phosphate transferase
essential
yes
ec
2.7.8.33
synonyms
yvhI

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.4|Biosynthesis of teichoic acid]
  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.3|Biosynthesis of teichoic acid]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • Gene

    Coordinates
    3,648,654 → 3,649,730

    Phenotypes of a mutant

  • essential [Pubmed|12682299]
  • The protein

    Catalyzed reaction/ biological activity

  • di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-α-D-glucosamine --> N-acetyl-α-D-glucosaminyl-1-diphospho-di-trans,octa-cis-undecaprenol + UMP (according to UniProt)
  • Protein family

  • glycosyltransferase 4 family (with [protein|4D3D4429E1F387BACB0D5A1084AA8DF179A16685|MraY], according to UniProt)
  • Structure

  • [PDB|4J72] (from Aquifex aeolicus, 28% identity) [pubmed|23990562]
  • [SW|Localization]

  • cell membrane (according to UniProt)
  • Expression and Regulation

    Operons

    genes
    [gene|D9257531C2E24426781342314953B89A8272C5E5|tagO]
    description
    [Pubmed|22383849]
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    References

    Reviews

  • 24024634
  • Original publications

  • 12101296,18156271,23986448,23990562