involved in arginine and ornithine utilization
function
arginine, ornithine and citrulline utilization
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.4|Utilization of arginine/ ornithine][SW|Categories] containing this gene/protein
[SW|utilization of amino acids]This gene is a member of the following [SW|regulons]
[SW|AhrC regulon], [SW|CodY regulon], [SW|RocR regulon], [SW|SigL regulon]Gene
Coordinates on the chromosome (coding sequence)
3,877,192 -> 3,878,892
The protein
Paralogous protein(s)
[protein|search|YqjN]Expression and Regulation
Operon
''[protein|search|rocA]-[protein|search|rocB]-[protein|search|rocC]'' [Pubmed|8113162][SW|Sigma factor]
[protein|search|SigL] [Pubmed|8113162]Regulation
induction by arginine ([protein|search|RocR], [protein|search|AhrC]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8113162,7565595 PubMed]repressed during growth in the presence of branched chain amino acids ([protein|search|CodY]) [Pubmed|12618455]Regulatory mechanism
[protein|search|CodY]: transcription repression [Pubmed|12618455][protein|search|RocR]: transcription activation [Pubmed|8113162][protein|search|AhrC]: transcription activation [Pubmed|7565595]Additional information
expression of the ''[protein|search|rocA]-[protein|search|rocB]-[protein|search|rocC]'' operon is increased upon depletion of ''[SW|nusA]'' (resulting from increased ''[SW|ahrC]'' expression) [http://www.nature.com/articles/nmicrobiol20157 Reference]References
