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yqcG [Sat Jan 28 2017 13:26:34 GMT+0100 (CET)]
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yqcG [Sat Jan 28 2017 13:26:34 GMT+0100 (CET)]

toxin, eliminates defective cells from developing biofilms, DNase activity
locus
BSU25860
pI
8.00
mw
59.00 kDa
function
eliminates defective cells from developing biofilms
product
toxin
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins] → [category|SW 4.3.17.2|Type 2 TA systems]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.18|Toxins, antitoxins and immunity against toxins/ based on similarity]
  • [category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.3|Skin element]
  • [SW|Categories] containing this gene/protein

  • [SW|toxins, antitoxins and immunity against toxins], [SW|Skin element]
  • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon], [SW|Spo0A regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,661,102 -> 2,662,697

    The protein

    Catalyzed reaction/ biological activity

  • part of a type II toxin/antitoxin system (with [SW|YqcF]) [Pubmed|27450630]
  • eliminates defective cells from developing biofilms [Pubmed|27450630]
  • DNA degradation [Pubmed|25922388]
  • Protein family

  • UPF0720 family (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|YqcG]-[protein|search|YqcF] [Pubmed|22200572]
  • Expression and Regulation

    Operon

  • ''[protein|search|yqcG]-[protein|search|yqcF]'' (according to [http://dbtbs.hgc.jp/COG/prom/yqcGF.html DBTBS])
  • Regulation

  • expressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|14651647]
  • strongly repressed in response to glucose starvation in M9 medium [Pubmed|23033921]
  • induced by amino acid limitation [Pubmed|27450630]
  • Regulatory mechanism

  • [SW|Spo0A]: transcription activation [Pubmed|14651647]
  • [protein|search|AbrB]: transcription repression [Pubmed|20817675]
  • References

  • 14651647,25922388,22200572,23033921,20817675,27450630