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yabM [Tue Dec 13 2016 11:16:29 GMT+0100 (CET)]
may function in a previously observed alternate pathway for peptidoglycan strand synthesis
function
alternate pathway for peptidoglycan strand synthesis
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins][SW|Categories] containing this gene/protein
[SW|cell wall synthesis], [SW|biosynthesis of cell wall components], [SW|membrane proteins]Gene
Coordinates on the chromosome (coding sequence)
64,817 -> 66,415
Phenotypes of a mutant
Mutants lacking YabM exhibit sensitivity to moenomycin, an antibiotic that blocks peptidoglycan polymerization by class A [[penicillin-binding proteins]]. [Pubmed|19648239]The protein
Catalyzed reaction/ biological activity
may function in a previously observed alternate pathway for peptidoglycan strand synthesis [Pubmed|19648239]Protein family
[SW|MOP exporter family]Paralogous protein(s)
[SW|SpoVB], [protein|search|YkvU], [protein|search|MurJ][SW|Localization]
cell membrane (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|yabM]-[protein|search|yabN]-[protein|search|yabO]-[protein|search|yabP]-[protein|search|yabQ]-[SW|divIC]-[protein|search|yabR]'' [Pubmed|11283287]References
11283287,19648239,19666716 
