bpr [Wed Jun 15 2016 16:32:45 GMT+0200 (CEST)]

bacillopeptidase F

locus: BSU15300

pI: 4.00

mw: 154.00 kDa

function: protein degradation

product: bacillopeptidase F

essential: no

synonyms: bpf

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.5|Utilization of proteins]
• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.7|Proteolysis] → [category|SW 3.3.7.2|Extracellular feeding proteases]
• [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]

[SW|Categories] containing this gene/protein

• [SW|utilization of nitrogen sources other than amino acids], [SW|proteolysis]

This gene is a member of the following [SW|regulons]

• [SW|DegU regulon]

Gene

Coordinates on the chromosome (coding sequence): 1,599,283 -> 1,603,584

The protein

Protein family

• peptidase S8 family (according to Swiss-Prot)

[SW|Localization]

• secreted (according to Swiss-Prot), extracellular (signal peptide) [Pubmed|18957862]

Expression and Regulation

Regulation

• repressed by glucose (7.7-fold) [Pubmed|12850135]

Regulatory mechanism

• [protein|search|DegU]-P: transcription activation [Pubmed|18194340]

Biological materials

Mutant

• BKE15300 (''ΔaprE::erm trpC2''), available at BGSC
• KO7 (''ΔnprE ΔaprE Δepr Δmpr ΔnprB Δvpr Δbpr''), available as BGSC 1A1133

References

Reviews

• 20735481

Original publications

• 2106512,18414485,18194340,24149708,18957862,12850135,24115457