N-acetylmuramoyl-L-alanine amidase
function
cell wall metabolism
product
N-acetylmuramoyl-L-alanine amidase
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.3|Cell wall degradation/ turnover] → [category|SW 1.1.3.1|Autolysis][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins][SW|Categories] containing this gene/protein
[SW|cell wall degradation/ turnover], [SW|sporulation proteins], [SW|membrane proteins]This gene is a member of the following [SW|regulons]
[SW|GerE regulon], [SW|SigK regulon]The protein
Catalyzed reaction/ biological activity
Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides (according to Swiss-Prot)Protein family
N-acetylmuramoyl-L-alanine amidase 2 family (according to Swiss-Prot)Paralogous protein(s)
[protein|search|CwlA], [protein|search|XlyA], [protein|search|XlyB][SW|Domains]
contains an amidase_2 domain (like [protein|search|BlyA], [protein|search|CwlA], [protein|search|XlyA], [protein|search|XlyB])[SW|Localization]
cell membrane (according to Swiss-Prot)Expression and Regulation
Operon
''[protein|search|cwlH]'' [Pubmed|10515909][SW|Sigma factor]
[protein|search|SigK] [Pubmed|10515909]Regulation
expressed late during sporulation in the mother cell ([protein|search|SigK], [protein|search|GerE]) [Pubmed|10515909]Regulatory mechanism
[protein|search|GerE]: transcription activation [Pubmed|10515909]References
