SubtiBank SubtiBank
pheA [Mon Feb 01 2016 11:06:48 GMT+0100 (CET)]
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pheA [Mon Feb 01 2016 11:06:48 GMT+0100 (CET)]

prephenate dehydratase
locus
BSU27900
pI
5.00
mw
31.00 kDa
function
biosynthesis of phenylalanine
product
prephenate dehydratase
essential
no
ec
4.2.1.51
synonyms

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.13|Biosynthesis/ acquisition of aromatic amino acids]
  • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis/ acquisition of amino acids]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,851,283 -> 2,852,140

    The protein

    Catalyzed reaction/ biological activity

  • Prephenate = phenylpyruvate H2O CO2 (according to Swiss-Prot)
  • Effectors of protein activity

  • subject to feedback inhibtion by phenylalanine [Pubmed|4956345]
  • Expression and Regulation

    Operon

  • ''[SW|spo0B]-[protein|search|obg]-[protein|search|yszB]-[protein|search|pheA]'' [Pubmed|22383849]
  • [SW|Sigma factor]

  • [protein|search|SigA] [Pubmed|2537815]
  • Additional information

  • subject to feedback inhibtion by phenylalanine [PubMed|4956345]
  • Biological materials

    Mutant

  • 1A617 ( ''pheA''::''erm''), [Pubmed|3015878], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A617&Search=1A617 BGSC]
  • References

  • 19258532,2537815,4956345