spoIIIJ [2017-07-18 09:52:02]

Sec-independent membrane protein translocase, essential for SigG activity at stage III, involved in the assembly of the SpoIIIAH-SpoIIQ complex

locus: BSU41040

pI: 9.99

mw: 29.37 kDa

protein length: 261 aa

gene length: 783 bp

function: membrane insertion of proteins and protein secretion

product: membrane protein translocase

essential: no

synonyms: spo0J87

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.3|Protein synthesis, modification and degradation] → [category|SW 3.3.5|Protein secretion]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.3|Sporulation/ other]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

Gene

Coordinates: 4,213,823 → 4,214,608

The protein

Catalyzed reaction/ biological activity

• membrane protein translocase, facilitates insertion of [protein|9D4AE9AE191BFA82791549852782DC1B959A6897|SpoIIIAE] into the membrane [Pubmed|18485064]

Protein family

• YidC/Oxa1/Alb3 family [Pubmed|20800571,21194367,15802250]

Paralogous protein(s)

• [protein|121A9543F5BC1CBE77D85A34099DE09F8AC63E9F|YidC2], one of the two proteins has to be present for viability [Pubmed|17114254]

[SW|Localization]

• membrane [Pubmed|18763711]

Expression and Regulation

Operons

• genes: [gene|EB07AECD3849CC0B65126DE27E71B28B3AD106B0|rpmH]-[gene|594F2D36BE71A45303A33AA2A2931F56F0A969ED|rnpA]-[gene|D40C202E67A5319A91811DB11356F47A56C97DD2|yidC1]-[gene|23D33E2D7AB1CA02165070DB8238957E3C768E64|jag]
  description: [Pubmed|22383849]

• genes: [gene|D40C202E67A5319A91811DB11356F47A56C97DD2|yidC1]-[gene|23D33E2D7AB1CA02165070DB8238957E3C768E64|jag]
  description: [Pubmed|1487728]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|1487728], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

  additional information

  • An [ncRNA|search|antisense RNA] is predicted for '[protein|search|jag]' [PubMed|20525796]

Labs working on this gene/protein

• [SW|Richard Losick], Harvard University, Cambridge, USA [http://www.mcb.harvard.edu/Losick/ homepage]
• [SW|Adriano Henriques], Lisbon, Portugal [http://www.itqb.unl.pt/research/biology/microbial-development homepage]

References

Reviews

• 22688815,20800571,21194367,15802250,25947384,27879020

Original publications

• 18485064,12813085,18820020,1487728,23852076,18763711,17114254,11889108,15995216,12586834,19717609,19779460,22864117,24443530,25133632,25313395,25359772,25855636,26331454