SubtiBank SubtiBank
azoR1 [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]
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azoR1 [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]

azoreductase, involved in quinone detoxification
locus
BSU19230
pI
4.00
mw
22.00 kDa
function
quinone detoxification
product
azoreductase
essential
no
synonyms
yocJ

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.8|Resistance against oxidative and electrophile stress]
  • [SW|Categories] containing this gene/protein

  • [SW|resistance against oxidative and electrophile stress], [SW|most abundant proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|YodB regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,096,350 -> 2,096,976

    The protein

    Paralogous protein(s)

  • [SW|AzoR2]
  • Structure

  • [PDB|3P0R] (from B. anthracis, 64% identity, 81% similarity)
  • Expression and Regulation

    Regulation

  • induced by thiol-reactive compounds (catechol, menaquinone) ([protein|search|YodB]) [Pubmed|18208493]
  • Regulatory mechanism

  • [protein|search|YodB]: transcription repression [Pubmed|18208493]
  • Additional information

  • belongs to the 100 [SW|most abundant proteins] [PubMed|15378759]
  • References

  • 18208493,17725564,15378759