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holA [2017-12-07 13:26:46]
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holA [2017-12-07 13:26:46]

DNA polymerase III, delta subunit, part of the clamp-loader complex and the replisome
locus
BSU25560
pI
6.23
mw
40.35 kDa
protein length
347 aa Sequence Blast
gene length
1041 bp Sequence Blast
function
DNA replication
product
DNA polymerase III, delta subunit
essential
yes
ec
2.7.7.7
synonyms
yqeN
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.1|DNA replication]
  • [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

    • Gene

    Coordinates
    2,636,096 → 2,637,139

    Phenotypes of a mutant

  • essential [Pubmed|12682299]

    • The protein

    Catalyzed reaction/ biological activity

  • required for bacteriophage SPP1 replication [Pubmed|23268446]

    • [SW|Domains]

  • domain I: aa 1 - 143, RecA-like fold [Pubmed|23525462]
  • domain II: aa 144 - 214, four alpha helices [Pubmed|23525462]
  • domain III: aa 215 - 339, seven alpha helices [Pubmed|23525462]

    • Structure

  • [PDB|3ZH9] [Pubmed|23525462]

    • [SW|Localization]

  • Nucleoid (Mid-cell) [Pubmed|16479537]

    • Expression and Regulation

    Operons

    genes
    [gene|CE70B471811371D454A74F67279974BF264205C2|holA]
    description
    [Pubmed|22383849]
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    References

  • 16479537,20122408,23525462,23268446,23563155