SubtiBank SubtiBank
fsrA
The second international online conference #Subtillery2021 will be held 14th - 18th June - save the date, for more information see the conference website!

The 21st International Conference on Bacilli has been postponed to 2022 and will take place in Prague.

fsrA

regulatory RNA
locus
BSU_misc_RNA_69
essential
no
synonyms
Outlinks

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.9|NcRNA] → [category|SW 6.9.5|Regulatory RNAs]
  • Gene

    Phenotypes of a mutant

  • transcription profile of a [gene|CE542AE1A32CCD1ABB259E6159F7A37A8078E189|fsrA] mutant strain: [http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE27416 GEO] [pubmed|22389480]
  • RNA

    basic information/Evolution

  • Catalyzed reaction/ biological activity: hybridizes to [gene|81429F7802CD4B1F7DFDB6C900D7DA5ECA6B9F3F|sdhC], [gene|E15E9F88B0E03FE8834C646369D2F4B4E713EF41|citB], [gene|57B9E37F6232189CD47C1B41FDCF43FCB8016AEB|lutB], [gene|44DF1B7E476AD58B3CCC39300FFE0132D0D32AD0|gltA]-[gene|AA07CC52B2DD48ACC9D3375E9D531CB1ACBE485A|gltB], and [gene|AC459429A9C50463FD947C1CF9EA919B6FE3B335|leuC]-[gene|0EB4C6EE398B14B9284FFAEDBC26C866CE2070D7|leuD] mRNAs and inhibits their translation [pubmed|18697947,22389480]
  • Expression and Regulation

    Operons

    genes
    [gene|CE542AE1A32CCD1ABB259E6159F7A37A8078E189|fsrA]
    description
    [pubmed|22383849]

    regulatory mechanism

  • [protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|Fur]: repression, [pubmed|18697947], in [regulon|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|Fur regulon]
  • regulation

  • induced by iron starvation (third wave, under extreme starvation, iron sparing response) ([protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|Fur]) [pubmed|29133393,18697947]
  • view in new tab

    Biological materials

    Mutant

  • HB7361 Δ[gene|CE542AE1A32CCD1ABB259E6159F7A37A8078E189|fsrA]::''cat'' (available in [SW|John Helmann]'s and [SW|Jörg Stülke]'s labs) [pubmed|18697947]
  • HB7385 Δ[gene|CE542AE1A32CCD1ABB259E6159F7A37A8078E189|fsrA]::''spc'' (available in [SW|John Helmann]'s and [SW|Jörg Stülke]'s labs) [pubmed|18697947]
  • labs

  • [SW|John Helmann], Cornell University, USA [http://www.micro.cornell.edu/research/labs/helmann-lab/index.cfm Homepage]
  • References

    Reviews

  • 32850966
  • Research papers

  • 22427629,18697947,22389480,29133393,32487739